Non-Coding RNAs

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Non-Coding RNAs

Non-coding RNAs are critical molecules that constitute a substantial amount of the transcriptome. We have witnessed an ever-increasing repository of non-coding RNAs (ncRNAs) in the last decade, especially with the large scale application of high throughput sequencing technologies. These ncRNAs include, but are not limited to, miRNAs, siRNAs, long non-coding RNAs (lncRNAs), circular intronic RNAs (ciRNAs) and circular RNAs (circRNAs) originated from back-spliced exons. ncRNAs have been demonstrated to involved in all important biological processes and human diseases. However, our understanding of these ncRNAs are still at the initial stages, especially for newly found ncRNAs such as lncRNAs, ciRNAs and circRNAs.

We thus would like to propose a Research Topic in Frontiers in Genetics to demonstrate recent progresses in the area of non-coding RNAs. The potential areas to include in the Research Topic include:

• What are the functions of ncRNAs?

• How do ncRNAs realize their functions?

• How are ncRNAs produced?

• How do you identify ncRNAs from high throughput sequencing data sets?

• How to predict the secondary structures of ncRNAs?

• What are the conservation patterns of ncRNAs?

• How to predict the potential functions of ncRNAs?

• What are the interactions between ncRNAs and other molecules?

• What are the mutations or editing events in ncRNAs and their significance in human diseases.

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Nimmi Anna
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Allied Journal of Medical Research
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