Nicotine replacement therapy and varenicline: A cohort study in low-income region (Monastir, Tunisia).

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Nicotine replacement therapy and varenicline: A cohort study in low-income region (Monastir, Tunisia).

 Background: Among motivated Smokers, cessation can be performed by Nicotine Replacement Therapy (NRT), or by Varenicline (VAR). We aimed at determining quit rates among two cohorts, treated by NRT or VAR and, at identifying factors associated to quit and relapse delays. Methods: We carried out a prospective cohort study at the smoking cessation center of the University Hospital of Monastir, in Tunisia from April 2009 to January 2012. Results: 1042 active smokers have been followed in smoking cessation center between April 2009 and December 2010. One hundred eighty two participants had met the inclusion criteria and had agreed to participate in our study. Abstinence rates, were, 61.5% at 3 month follow up and 36.3% at one year (p=001). After adjusting on age, alcohol consumption, anxiety scale, and exhaled carbon monoxide values, there were no significant differences on abstinence rates in two groups NRT or VAR. In multivariate analysis, factors associated to a precipitate smoking relapse were presence of anterior previous attempts (HR: 0.10; 95% CI: 0.030-0.328), living with smokers at home (HR: 2.541; 95% CI: 1.019-6.336), having five following visits (HR: 0.091; 95% CI: 0.017-0.500) and having minimal withdrawal syndrome reveled on follow up (HR: 0.23; 95% CI: 0.08-0.662). Whereas, factors associated to quit delay was the use of NRT at the expense of VAR (HR: 4.966; 95% CI: 2.81-8.76). Conclusions: Relapse was not associated to treatment classes, whereas NRT have the benefit of a longer quit duration.
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Nimmi Anna
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Allied Journal of Medical Research
Email: medicalresearch@emedsci.com

Nicotine replacement therapy and varenicline: A cohort study in low-income region (Monastir, Tunisia).

 Background: Among motivated Smokers, cessation can be performed by Nicotine Replacement Therapy (NRT), or by Varenicline (VAR). We aimed at determining quit rates among two cohorts, treated by NRT or VAR and, at identifying factors associated to quit and relapse delays. Methods: We carried out a prospective cohort study at the smoking cessation center of the University Hospital of Monastir, in Tunisia from April 2009 to January 2012. Results: 1042 active smokers have been followed in smoking cessation center between April 2009 and December 2010. One hundred eighty two participants had met the inclusion criteria and had agreed to participate in our study. Abstinence rates, were, 61.5% at 3 month follow up and 36.3% at one year (p=001). After adjusting on age, alcohol consumption, anxiety scale, and exhaled carbon monoxide values, there were no significant differences on abstinence rates in two groups NRT or VAR. In multivariate analysis, factors associated to a precipitate smoking relapse were presence of anterior previous attempts (HR: 0.10; 95% CI: 0.030-0.328), living with smokers at home (HR: 2.541; 95% CI: 1.019-6.336), having five following visits (HR: 0.091; 95% CI: 0.017-0.500) and having minimal withdrawal syndrome reveled on follow up (HR: 0.23; 95% CI: 0.08-0.662). Whereas, factors associated to quit delay was the use of NRT at the expense of VAR (HR: 4.966; 95% CI: 2.81-8.76). Conclusions: Relapse was not associated to treatment classes, whereas NRT have the benefit of a longer quit duration.
I would like to know your interest and time in submitting an article for the upcoming issue of 2020.

You may submit your papers as an attachment to this email or online at: https://www.scholarscentral.org/submission/allied-medical-research.html.

How we work:

  • After submission, an acknowledgement with manuscript number is sent to the corresponding author within 7 working days.
  • A 21 day window time frame is allotted for peer-review process wherein multiple experts are contacted.
  • Author proof is generated within 7 working days after the acceptance decision.

Benefits on Publication:

Open Access: Permanent free access to your article upon publication ensures extensive global reach and readership.

Easy Article Sharing: Our open access enables you to share your article directly with colleagues through email and on social media via a single link, permitting third party reuse with appropriate citation in addition to the retention of content copyright by the author.

Global Marketing: Through promotion in a targeted global email announcement or press release, your article will be seen by thousands of the top-most thought-leaders in your field.

Color Art: In a world of black & white journal articles, high-quality full-color images make your article stand out from the crowd and tell a complete story, increasing readers and citations.

Social Media Exposure: Extended reach for your article through links on Twitter accounts provides maximum visibility worldwide.

Reprints: Distribute your work to colleagues and at conferences as we provide hard copy color reprints of your article on order.

Media Contact:
Nimmi Anna
Journal Manager
Allied Journal of Medical Research
Email: medicalresearch@emedsci.com